Supplementary material from "Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm"

In this paper, the signal-to-noise ratios (SNR) of the two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNRs to achieve a better image processing effect, two sources white light and near-infrared light of fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was set-up to acquire endoscopic images of target dyed by indocyanine green (ICG). The experimental results showed that the SNRs of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNRs of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNRs of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by applied the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescent, effectively enhance the SNRs of white and fluorescent images, and improve the imaging quality.