Supplementary data 1 from Geometric constraint of mechanosensing by modification of hydrogel thickness prevents stiffness-induced differentiation in bone marrow stromal cells
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journal contribution
posted on 2024-10-28, 07:28authored byMaria L Hernandez-Miranda, Dichu Xu, Aya A Ben Issa, David A Johnston, Martin Browne, Richard B Cook, Bram G Sengers, Nicholas D Evans
A summary of computer simulations conducted to explore how the lateral stiffness experienced during cell contraction (defined as the ratio between lateral force and displacement), depends on gel thickness and constraints imposed by neighbouring cells pulling in opposite directions.