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Supplementary Material Information from The surface adsorption, aggregate structure and antibacterial activity of Gemini quaternary ammonium surfactants with carboxylic counterions

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journal contribution
posted on 10.08.2019 by Xiqin Zhou, Siqi Hu, Yu Wang, Sana Ullah, Jun Hu, Hongqin Liu, Baocai Xu
A group of Gemini quaternary ammonium surfactants with the formula CnH2n+1CONH(CH2)2N+(CH3)2(CH2)2N+(CH3)2(CH2)2NHCOCnH2n+1 · 2Y (n = 11, 13 and 15, Y = HCOO, CH3COO and CH3CHOHCOO) have been synthesized by a counterion conversion process and characterized by a Fourier transform infrared spectroscopy and a mass spectroscopy. Their adsorption and self-aggregation properties are investigated by surface tension, conductivity, dynamic light scattering and transmission electron microscopy (TEM) measurements. The results show that these surfactants reduce the surface tension of water to a minimum value of 26.51 mN m−1 at a concentration of 5.72 × 10−2 mmol l−1. Furthermore, the increased alkyl chain length of the carboxylic counterions leads to the increased critical micelle concentration, the decreased degree of counterion binding (β) and the decreased self-assembly tendency, but the minimum area per surfactant molecule (Amin) adsorbed at the air–aqueous solution are similar. TEM images reveal that these surfactants self-assemble spontaneously into aggregates with vesicle or bilayer structures. It is also found that they have superior antibacterial activity at a concentration of 0.1 g l−1. The high surface activity and high antibacterial activity of the Gemini quaternary ammonium salt surfactants containing different carboxylic counterions bring more possibilities for the application in the field of biomedicine.