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The EGFR/MEK/ERK and PI3K/AKT pathways abrogation do not affect basal pirin levels in OKF6-Tert2 from Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells

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posted on 31.10.2017, 16:40 authored by Diego Carrillo, Juan P. Muñoz, Hernán Huerta, Gabriel Leal, Alejandro Corvalán, Oscar León, Gloria M. Calaf, Ulises Urzúa, Enrique Boccardo, Julio C. Tapia, Francisco Aguayo
(a) OKF6-Tert2 cells stably transfected with pLXSN vector were incubated with inhibitors AG1478 (EGFR tyrosine kinase), UO126 (MEK1/MEK2) and LY294002 (phosphoinositide 3-kinase). Pirin protein levels were evaluated by Western blot.