Supplementary Figure 1 from Investigating the mechanistic basis of biomechanical input controlling skeletal development: exploring the interplay with Wnt signalling at the joint

The developing cartilaginous skeleton. 3D analysis of the expression pattern of Col2a1 in whole chick embryos (a-e) across stages HH26-HH30, Lateral views of volume rendered 3D reconstructions of the data following OPT scanning (expressing tissues appear white/grey). Matching lateral views of surface rendered data (expression shown in yellow). Red brackets show separation of Col2a1 expression in the mid-diaphysis of the rudiment at HH30. fl, forelimb, hl, hindlimb, s, scapula; h, humerus; u, ulna; r, radius; tt, tibiotarsus; fe, femur; fb, fibula.