HPV-16 E6 and E7 oncoproteins are functional in oral OKF6 cells from Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells

(a) OKF6 cells were transiently transfected with pLXSNHPV16E6 (right), pLXSNHPV16E7 (left) or empty pLXSN vector and p53 or pRb proteins were evaluated through Western blot. Results are representative of three independent experiments. (b) Relative viral load in SiHa and Ca Ski cells determined by qPCR.