rsif20180125_si_004.xlsx (376.92 kB)

Supplementary File S3 from Integrated human-virus metabolic stoichiometric modelling predicts host-based antiviral targets against Chikungunya, Dengue and Zika viruses

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posted on 11.09.2018 by Sean Aller, Andrew Scott, Mitali Sarkar-Tyson, Orkun S. Soyer
Results for the reaction knockout and host-derived enforcement analyses. Model reactions and model subsystems are listed. The resulting virus optima, for CHIKV, DENV and ZIKV, are shown as a percentage of the original model (without the additional constraints imposed by the analyses). The lower and upper flux bounds used for the host-derived enforcement analysis are listed for the relevant reaction and associated virus optimisation result.