rsob190273_si_008.avi (7.59 MB)
Movie S7 from Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42
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posted on 2020-03-16, 05:07 authored by I-Chen Hung, Tsung-Ming Chen, Jing-Ping Lin, Yu-Ling Tai, Tang-Long Shen, Shyh-Jye LeeTime-lapse imaging of cell migration in lateral hypoblast of fak1a morphant inject into un-injected wildtype host A fluorescence time-lapse image of lateral hypoblast of fak1a MO and rhodamine-injected cell transplanted into un-injected wildtype host, showing the normal cell migration during epiboly. The image was taken a period of 30 min with a frame taken every 10 sec. Compare the cell migration in the movie with Supplementary Movies S8 to show the high cell migration rate in cell injected into un-injected wildtype host versus the fak1a morphant host. The hypoblasts were migrating dorsally to the bottom right corner.