Synthetic and biological experiments from N<i><sup>ε</sup></i>-acetyl-lysine derivatives with zinc binding groups as novel HDAC inhibitors Fang Wang Chun Wang Jie Wang Yefang Zou Xiaoxue Chen Ting Liu Yan Li Yonglong Zhao Yongjun Li Bin He 10.6084/m9.figshare.8152961.v1 https://rs.figshare.com/articles/journal_contribution/Synthetic_and_biological_experiments_from_N_i_sup_sup_i_-acetyl-lysine_derivatives_with_zinc_binding_groups_as_novel_HDAC_inhibitors/8152961 HDAC inhibitors have been developed very rapidly in clinical trials and even in approvals for treating several cancers. However, there are few reported HDAC inhibitors designed from N<sup>ε</sup>-acetyl lysine. In current study, we raised a novel design, which is about N<sup>ε</sup>-acetyl lysine derivatives containing amide acetyl groups with the hybridization of ZBG groups as novel HDAC inhibitors. 2019-05-20 11:10:03 Nε-acetyl lysine ZBG group analogues hybridization HDAC inhibitor