%0 Generic %A Aller, Sean %A Scott, Andrew %A Sarkar-Tyson, Mitali %A S. Soyer, Orkun %D 2018 %T Supplementary File S4 from Integrated human-virus metabolic stoichiometric modelling predicts host-based antiviral targets against Chikungunya, Dengue and Zika viruses %U https://rs.figshare.com/articles/dataset/Supplementary_File_S4_from_Integrated_human-virus_metabolic_stoichiometric_modelling_predicts_host-based_antiviral_targets_against_Chikungunya_Dengue_and_Zika_viruses/7012430 %R 10.6084/m9.figshare.7012430.v1 %2 https://rs.figshare.com/ndownloader/files/12866264 %K emerging viruses %K antiviral targets %K flux balance analysis %K host–virus interactions %K metabolic modelling %X A list of model reactions identified from the host-enforcement analysis that are able to reduce one of the three viruses, CHIKV, DENV and ZIKV, to below 80% of the original virus optima in the original model (without additional constraints). Inhibitors are listed for the respective reactions and were identified through the Brenda Enzymatic Database via the Enzyme Commission Number associated with the reaction. %I The Royal Society