Figure S2 from Human transposon insertion profiling by sequencing (TIPseq) to map LINE-1 insertions in single cells Wilson McKerrow Zuojian Tang Jared P. Steranka Lindsay M. Payer Jef D. Boeke David Keefe David Fenyƶ Kathleen H. Burns Chunhong Liu 10.6084/m9.figshare.11450001.v1 https://rs.figshare.com/articles/journal_contribution/Figure_S2_from_Human_transposon_insertion_profiling_by_sequencing_TIPseq_to_map_LINE-1_insertions_in_single_cells/11450001 Comparison of sensitivity for all gold standard L1Hs and only heterozygous non-reference insertions. Black, bulk DNA TIPseq; red, MDA whole genome amplification followed by restriction enzyme digestion and ligation with vectorette adaptors (MDA-D); orange, MDA whole genome amplification followed by end repair, dA tailing and ligation with dT vectorette adaptor (MDA-T); dark blue, MALBAC whole genome amplification followed by ligation with dT vectorette adaptor (MALBAC-T). Diamond, bulk DNA TIPseq; circle, whole genome amplification using random hexamers only (R); square, whole genome amplification using random hexamers and L1 primer (RL). 2019-12-24 16:16:56 mobile genetic element retrotransposon TIPseq whole-genome amplification somatic mosaicism tumour heterogeneity