%0 Generic
%A Baller, Daniel
%A Thomas, Diana M.
%A Cummiskey, Kevin
%A Bredlau, Carl
%A Schwartz, Nadav
%A Orzechowski, Kelly
%A Miller, Richard C.
%A Odibo, Anthony
%A Shah, Ruchit
%A Salafia, Carolyn M.
%D 2019
%T For Dan WUSTL.xlsx from Gestational growth trajectories derived from a dynamic fetal–placental scaling law
%U https://rs.figshare.com/articles/dataset/For_Dan_WUSTL_xlsx_from_Gestational_growth_trajectories_derived_from_a_dynamic_fetal_placental_scaling_law/10047368
%R 10.6084/m9.figshare.10047368.v1
%2 https://rs.figshare.com/ndownloader/files/18107402
%K placenta
%K placental volume
%K differential equation
%K logistic growth model
%K fetal growth curves
%K nonlinear regression
%X Fetal trajectories characterizing growth rates in utero have relied primarily on goodness of fit rather than mechanistic properties exhibited in utero. Here, we use a validated fetal–placental allometric scaling law and a first principles differential equations model of placental volume growth to generate biologically meaningful fetal–placental growth curves. The growth curves form the foundation for understanding healthy versus at-risk fetal growth and for identifying the timing of key events in utero.
%I The Royal Society